Vitronectin / Unconjugated / 5G11B10D7

Product Details
Supplier Sino Biological
Catalog #: 10424-MM11 (View supplier product page)
Size 100 μl
Price $149.00
Antigen Vitronectin
Clone 5G11B10D7
Host Mouse
Isotype IgG2a
Conjugate Unconjugated
Target Species Human
Applications ELISA
Description This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Vitronectin (rh Vitronectin; Catalog#10424-H07H; NP_000629.3; Asp 20-Leu 478). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography .
About Vitronectin and Purified
Vitronectin The protein encoded by this gene functions in part as an adhesive glycoprotein. Differential expression of this protein can promote either cell adhesion or migration as it links cells to the extracellular matrix through a variety of ligands. These ligands include integrins, plasminogen activator inhibitor-1, and urokinase plasminogen activator receptor. This secreted protein can be present in the plasma as a monomer or dimer and forms a multimer in the extracellular matrix of several tissues. This protein also inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpin serine protease inhibitors. This protein can also promote extracellular matrix degradation and thus plays a role in tumorigenesis. It is involved in a variety of other biological processes such as the regulation of the coagulation pathway, wound healing, and tissue remodeling. The heparin-binding domain of this protein give it anti-microbial properties. It is also a lipid binding protein that forms a principal component of high density lipoprotein. [provided by RefSeq, Aug 2020]
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Purified Excitation and Emission Spectra