Cystatin E/M / Unconjugated / 17

Product Details
Supplier Sino Biological
Catalog #: 10438-MM17 (View supplier product page)
Size 100 μl
Price $149.00
Antigen Cystatin E/M
Clone 17
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human
Applications IHC-P
Description This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Cystatin E / CST6 (rh Cystatin E / CST6; Catalog#10438-H08H; NP_001314.1; Met1-Met149). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
About Cystatin E/M and Purified
Cystatin E/M The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra