CD45 / Unconjugated / GC6A

Product Details
Supplier Boster Biological Technology
Catalog #: V00555-6 (View supplier product page)
Size 100 μg
Price $299.00
Antigen CD45
Clone GC6A
Host Mouse
Isotype IgM
Conjugate Unconjugated
Target Species Bison, Bovine, Caprine
Applications Cell Function, FC, IHC
Description Mouse IgM monoclonal antibody for CD45R detection. Tested with FCM, IHC, Cell Function in Bison;Bovine;Caprine;Ovine.
About CD45 and Purified
CD45 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
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Purified Excitation and Emission Spectra