PRKAB2 / DyLight 488 / 6G1

Product Details
Supplier Boster Biological Technology
Catalog #: M05077-Dyl488 (View supplier product page)
Size 100 μg
Price $290.00
Antigen PRKAB2
Clone 6G1
Host Mouse
Isotype IgG2b
Conjugate DyLight 488
Target Species Human
Applications FC
Description Mouse IgG Monoclonal Anti-Human AMPK beta 2 Antibody DyLight® 488 Conjugated, Flow Validated.
About PRKAB2 and DyLight 488
PRKAB2 The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra