Vimentin Monoclonal / DyLight 755 / RV202

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-97672IR (View supplier product page)
Size 0.1 ml
Price $559.00
Antigen Vimentin
Clone RV202
Host Mouse
Isotype IgG1
Conjugate DyLight 755
Target Species Canine, Chicken, Goat, Hamster, Human, Mouse, Porcine, Primate, Rat, Xenopus, Zebrafish
Applications WB, FC, IHC, ICC/IF, IHC-P, IHC-Fr
Description RV202 reacts exclusively with vimentin, which is expressed in mesenchymal cells and mesenchymal derived tumors e.g. lymphoma, sarcoma and melanoma.
About Vimentin and DyLight 755
Vimentin This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra