CD106 Monoclonal / HRP / MVCAM A (429)

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-50620H (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen CD106
Clone MVCAM A (429)
Host Rat
Isotype IgG
Conjugate HRP
Target Species Mouse
Applications IHC-Fr, IHC
Description Recognizes murine vascular adhesion molecule 1 (VCAM-1), a cell surface glycoprotein that is also known as CD106. CD106 is expressed predominantly on endothelial cells and expression is up-regulated during inflammation. The ligand for CD106 is the alpha 4 subunit (CD49d) of the integrin VLA-4 (CD49d/CD29). Clone MVCAM.A(429) is reported to partially block VCAM-1 mediated functions.
About CD106 and HRP
CD106 This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]
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HRP Excitation and Emission Spectra