FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP2-57503 (View supplier product page)
	Size	100 ul
	Price	$519.00
	Antigen	SLC22A18
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human
	Applications	IHC, IHC-P
	Description	Specificity of human Solute carrier family 22 member 18 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

	SLC22A18	This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Several alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2015]

		Immunohistochemistry-Paraffin: Solute carrier family 22 member 18 Antibody [NBP2-57503] - Staining in human small intestine and liver tissues using anti-SLC22A18 antibody. Corresponding SLC22A18 RNA-seq data are presented for the same tissues.
		Immunohistochemistry-Paraffin: Solute carrier family 22 member 18 Antibody [NBP2-57503] - Staining of human small intestine shows high expression.
		Immunohistochemistry-Paraffin: Solute carrier family 22 member 18 Antibody [NBP2-57503] - Staining of human liver shows low expression as expected.