RNASEH2A Polyclonal / Unconjugated /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-58235-20ul (View supplier product page)
Size 20ul
Price $169.00
Antigen RNASEH2A
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications WB, IHC, IHC-P
Description This product is specific to Subunit or Isoform: A.
About RNASEH2A and Purified
RNASEH2A The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]
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Purified Excitation and Emission Spectra