RNASEH2A Polyclonal / Unconjugated /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-32143 (View supplier product page)
Size 100 μl
Price $379.00
Antigen RNASEH2A
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IP
Description RNASEH2A Antibody
About RNASEH2A and Purified
RNASEH2A The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]
Images
  RNASEH2A Purified Novus Biologicals, a Bio-Techne brand antibody anti target:Human host:Rabbit isotype:IgG clone: Immunoprecipitation: RNASEH2A Antibody [NBP2-32143] - Samples:  Whole cell lysate (1 mg for IP; 2...

Immunoprecipitation: RNASEH2A Antibody [NBP2-32143] - Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from Jurkat cells. Antibodies: Affinity purified rabbit anti-RNASEH2A antibody NBP2-32143 used for IP at 6 ug/mg lysate. For blotting immunoprecipitated RNASEH2A was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

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Purified Excitation and Emission Spectra