FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP1-80908 (View supplier product page)
	Size	0.1 ml
	Price	$519.00
	Antigen	PIK3C2A
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human
	Applications	IHC, IHC-P
	Description	Specificity of human PIK3C2A antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

	PIK3C2A	The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]