PCDHGA1 Monoclonal / Alexa Fluor 700 / S159-5

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-42207AF700 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen PCDHGA1
Clone S159-5
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 700
Target Species Human, Mouse, Rat
Applications WB, IHC
Description Detects approx 100kDa. Cross-reacts with all Gamma-protocadherin-A, -B and -C proteins.
About PCDHGA1 and Alexa Fluor 700
PCDHGA1 This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra