FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP2-47337 (View supplier product page)
	Size	0.1 ml
	Price	$519.00
	Antigen	PARP2
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human
	Applications	WB, IHC, ICC/IF, IHC-P
	Description	Specificity of human PARP2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

	PARP2	This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]

		Immunohistochemistry-Paraffin: PARP2 Antibody [NBP2-47337] - Staining of human pancreas shows no positivity in exocrine glandular cells.
		Western Blot: PARP2 Antibody [NBP2-47337] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Human cell line U-2 OS
		Immunocytochemistry/Immunofluorescence: PARP2 Antibody [NBP2-47337] - Immunofluorescent staining of human cell line MCF7 shows localization to nucleus.
		Immunohistochemistry-Paraffin: PARP2 Antibody [NBP2-47337] - Staining in human testis and pancreas tissues.. Corresponding PARP2 RNA-seq data are presented for the same tissues.
		Immunohistochemistry-Paraffin: PARP2 Antibody [NBP2-47337] - Staining of human testis shows moderate nuclear positivity in cells in seminiferous ducts.