Pappalysin-1 Monoclonal / Biotin / 9

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-05116B (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen Pappalysin-1
Clone 9
Host Mouse
Isotype IgG1 κ
Conjugate Biotin
Target Species Human
Applications ELISA, IHC, IHC-P, WB, IHC-Fr
Description Specific for native human PAPP-A. Heat and SDS denatured PAPP-A is also recognized, but not acid treated PAPP-A.
About Pappalysin-1 and Biotin
Pappalysin-1 This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. [provided by RefSeq, Aug 2017]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Biotin Excitation and Emission Spectra