ORC1 Polyclonal / Unconjugated /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-24600 (View supplier product page)
Size 0.1 mg
Price $339.00
Antigen ORC1
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse
Applications WB
Description Rabbit ORC1 antibody [Purified] detects Human, Mouse
About ORC1 and Purified
ORC1 The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
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  ORC1 Purified Novus Biologicals, a Bio-Techne brand antibody anti target:Human, Mouse host:Rabbit isotype:IgG clone: Western Blot: ORC1 Antibody [NBP2-24600] - Analysis of ORC1L in Daudi cell lysate in the 1) absen...

Western Blot: ORC1 Antibody [NBP2-24600] - Analysis of ORC1L in Daudi cell lysate in the 1) absence and 2) presence of immunizing peptide and in 3) NIH 3T3 cell lysate using NBP2-24600. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
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Purified Excitation and Emission Spectra