FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP2-42048 (View supplier product page)
	Size	0.1 ml
	Price	$519.00
	Antigen	REST
	Clone	CL0381
	Host	Mouse
	Isotype	IgG1
	Conjugate	Unconjugated
	Target Species	Human
	Applications	IHC, IHC-P, ICC/IF
	Description	Specificity of human NRSF antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

	REST	This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2018]

		Immunohistochemistry-Paraffin: NRSF Antibody (CL0381) [NBP2-42048] - Staining of human cerebral cortex shows no nuclear positivity in neuronal cells as expected.
		Immunohistochemistry-Paraffin: NRSF Antibody (CL0381) [NBP2-42048] - Staining of human tonsil shows moderate to strong nuclear positivity in lymphoid cells.
		Immunohistochemistry-Paraffin: NRSF Antibody (CL0381) [NBP2-42048] - Staining of human testis shows moderate to strong nuclear positivity in cells in seminiferous ducts.
		Immunohistochemistry-Paraffin: NRSF Antibody (CL0381) [NBP2-42048] - Staining of human endometrium shows moderate nuclear positivity in glandular and stromal cells.