FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP2-48752 (View supplier product page)
	Size	0.1 ml
	Price	$519.00
	Antigen	NOD2
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human
	Applications	WB, IHC, IHC-P
	Description	Specificity of human NOD2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

	NOD2	This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

		Immunohistochemistry-Paraffin: NOD2 Antibody [NBP2-48752] - Staining of human skin shows moderate to strong cytoplasmic positivity in keratinocytes.
		Immunohistochemistry-Paraffin: NOD2 Antibody [NBP2-48752] - Staining of human rectum shows strong cytoplasmic positivity in glandular cells.
		Immunohistochemistry-Paraffin: NOD2 Antibody [NBP2-48752] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.
		Immunohistochemistry-Paraffin: NOD2 Antibody [NBP2-48752] - Analysis in human skin and kidney tissues. Corresponding NOD2 RNA-seq data are presented for the same tissues.
		Western Blot: NOD2 Antibody [NBP2-48752] - Analysis using Anti-NOD2 antibody NBP2-48752 (A) shows similar pattern to independent antibody NBP2-58617 (B).
		Immunohistochemistry-Paraffin: NOD2 Antibody [NBP2-48752] - Staining of human kidney shows no positivity in cells in tubules as expected.