NGF Receptor/p75NTR (CD271) Monoclonal / Unconjugated / NGFR5

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-48295 (View supplier product page)
Size 7 ml
Price $419.00
Antigen NGF Receptor/p75NTR (CD271)
Clone NGFR5
Host Mouse
Isotype IgG1 κ
Conjugate Unconjugated
Target Species Baboon, Feline, Ferret, Human, Monkey, Mouse (Negative), Rabbit, Rat (Negative)
Applications IHC-P, IHC
Description It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
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Purified Excitation and Emission Spectra