Neuropeptide Y Monoclonal / Janelia Fluor 549 / 8

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-05166JF549 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen Neuropeptide Y
Clone 8
Host Mouse
Isotype IgG1 κ
Conjugate Janelia Fluor 549
Target Species Human, Mouse, Rat
Applications IHC, ICC/IF, IHC-P, ELISA
Description Binds full length human/rat NPY. Cross-reactivity with NPY (1-24), NPY (18-36), PYY or PP was <0.2%.
About Neuropeptide Y and Janelia Fluor 549
Neuropeptide Y This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
Janelia Fluor 549 Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.
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Janelia Fluor 549 Excitation and Emission Spectra