FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP1-82763 (View supplier product page)
	Size	0.1 ml
	Price	$519.00
	Antigen	MRPL45
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human
	Applications	WB, IHC, ICC/IF, IHC-P
	Description	Specificity of human MRPL45 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

	MRPL45	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q. [provided by RefSeq, May 2013]

		Immunohistochemistry-Paraffin: MRPL45 Antibody [NBP1-82763] - Staining of human liver.
		Immunohistochemistry-Paraffin: MRPL45 Antibody [NBP1-82763] - Staining of human colon.
		Immunohistochemistry-Paraffin: MRPL45 Antibody [NBP1-82763] - Staining of human colon, kidney, liver and testis using Anti-MRPL45 antibody NBP1-82763 (A) shows similar protein distribution across tissues to independent antibody NBP1-82764 (B).
		Western Blot: MRPL45 Antibody [NBP1-82763] - Analysis using Anti-MRPL45 antibody NBP1-82763 (A) shows similar pattern to independent antibody NBP1-82764 (B).
		Immunohistochemistry-Paraffin: MRPL45 Antibody [NBP1-82763] - Staining of human kidney.
		Immunohistochemistry-Paraffin: MRPL45 Antibody [NBP1-82763] - Staining of human testis.
		Immunocytochemistry/Immunofluorescence: MRPL45 Antibody [NBP1-82763] - Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
		Immunohistochemistry-Paraffin: MRPL45 Antibody [NBP1-82763] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.