MMP-9 Monoclonal / Alexa Fluor 488 / S51-82

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-59699AF488 (View supplier product page)
Size 100 ul
Price $549.00
Antigen MMP-9
Clone S51-82
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 488
Target Species Human, Mouse, Rat
Applications WB, ICC/IF
Description Detecs ~92kDa and ~82kDa (pro and active forms).
About MMP-9 and Alexa Fluor 488
MMP-9 Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra