MED12 Polyclonal / Alexa Fluor 700 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-2357AF700 (View supplier product page)
Size 100 ul
Price $549.00
Antigen MED12
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 700
Target Species Human, Mouse, Primate
Applications WB, IHC, ICC/IF, IHC-P
Description Rabbit MED12 antibody reacts with Human, Mouse, Primate [Alexa Fluor 700]
About MED12 and Alexa Fluor 700
MED12 The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. [provided by RefSeq, Aug 2009]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra