CD146 Monoclonal / HRP / OJ79c

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-34701H (View supplier product page)
Size 100 μl
Price $429.00
Antigen CD146
Clone OJ79c
Host Mouse
Isotype IgG1 κ
Conjugate HRP
Target Species Human
Applications WB, ELISA, IHC-Fr, IHC
Description The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
About CD146 and HRP
CD146 Involved in glomerular filtration and vascular wound healing. Acts upstream of or within angiogenesis. Located in external side of plasma membrane. Biomarker of chronic obstructive pulmonary disease and uveal melanoma. [provided by Alliance of Genome Resources, Apr 2022]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

HRP Excitation and Emission Spectra