MAPK10 Monoclonal / Unconjugated / 4E12-1F7

Citations: (1)
Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: H00005602-M01 (View supplier product page)
Size 0.1 mg
Price $519.00
Antigen MAPK10
Clone 4E12-1F7
Host Mouse
Isotype IgG1 κ
Conjugate Unconjugated
Target Species Human
Applications WB, ELISA, ICC/IF, PLA
Description MAPK10 - mitogen-activated protein kinase 10
About MAPK10 and Purified
MAPK10 The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
Citations
PMID 25807892
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Purified Excitation and Emission Spectra