FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP1-51544 (View supplier product page)
	Size	0.1 ml
	Price	$449.00
	Antigen	MAPK10
	Clone	10E4A4
	Host	Mouse
	Isotype	IgG1
	Conjugate	Unconjugated
	Target Species	Human, Mouse
	Applications	WB, ELISA, ICC/IF
	Description	Mouse JNK3 antibody reacts with Human, Mouse [Purified]

	MAPK10	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals, and thus are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system, and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

		Western Blot: JNK3 Antibody (10E4A4) [NBP1-51544] - Western blot analysis using MAPK10 mouse mAb against NIH/3T3 (1) and SKN-SH (2) cell lysate.
		Immunocytochemistry/Immunofluorescence: JNK3 Antibody (10E4A4) [NBP1-51544] - Immunofluorescence staining of methanol-fixed A431 (left) and Hela (right) cells showing cytoplasmic and membrane localization.