FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP2-03989 (View supplier product page)
	Size	100 μl
	Price	$263.00
	Antigen	HDAC5
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human, Mouse, Rat
	Applications	WB, IHC, IHC-P
	Description	Prepared from rabbit serum by affinity purification via sequential chromatography on phospho and dephosphopeptide affinity columns.

	HDAC5	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

		Western Blot: HDAC5 Antibody [NBP2-03989] - Aanalysis of HDAC5 (Ab-498) (Lanes 1 and 2) using NBP2-03989 in NIH/3T3 cells.
		Immunohistochemistry-Paraffin: HDAC5 Antibody [NBP2-03989] - Analysis of HDAC5 in paraffin-embedded human breast carcinoma tissue using this antibodies