Haptoglobin Polyclonal / Unconjugated /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-64425 (View supplier product page)
Size 1 ml
Price $299.00
Antigen Haptoglobin
Clone
Host Sheep
Isotype IgG
Conjugate Unconjugated
Target Species Bovine (Negative), Canine, Chicken (Negative), Equine, Feline, Guinea Pig (Negative), Human, Mouse, Porcine, Rabbit, Rat
Applications RID
Description Recognizes haptoglobulin, a plasma protein that has high affinity for haemoglobin.
About Haptoglobin and Purified
Haptoglobin This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra