FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP2-41159 (View supplier product page)
	Size	0.1 mg
	Price	$399.00
	Antigen	GRB10
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human, Mouse, Rat
	Applications	WB, ELISA, ICC/IF
	Description	At least three isoforms of GRB10 are known to exist; this antibody will detect all three isoforms.

	GRB10	The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]

		Immunocytochemistry/Immunofluorescence: GRB10 Antibody [NBP2-41159] - Immunofluorescence of GRB10 in rat brain cells with GRB10 antibody at 20 ug/mL.
		Western Blot: GRB10 Antibody [NBP2-41159] - Western blot analysis of GRB10 in SK-N-SH cell lysate with GRB10 antibody at (A) 1 and (B) 2 ug/mL.