GSTM1 Monoclonal / Unconjugated / 1H7.D8.G5
GSTM1 Monoclonal / Unconjugated / 1H7.D8.G5
Product Details
| Supplier | Novus Biologicals, a Bio-Techne brand | |
|---|---|---|
| Catalog #: | NBP2-44180 (View supplier product page) | |
| Size | 0.1 mg | |
| Price | $549.00 | |
| Antigen | GSTM1 | |
| Clone | 1H7.D8.G5 | |
| Host | Mouse | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse | |
| Applications | WB, ELISA, IHC, IP |
About GSTM1 and Purified
| GSTM1 | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008] |
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Images
![GSTM1 Purified Novus Biologicals, a Bio-Techne brand antibody anti target:Human, Mouse host:Mouse isotype:IgG clone:1H7.D8.G5 Western Blot: Glutathione S-Transferase mu 1/GSTM1 Antibody [NBP2-44180] - Lane 1: rGSTM1 protein...](http://images.novusbio.com/images2/Glutathione-S-Transferase-mu-1-GSTM1-Antibody-Western-Blot-NBP2-44180-img0001.jpg)
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Western Blot: Glutathione S-Transferase mu 1/GSTM1 Antibody [NBP2-44180] - Lane 1: rGSTM1 protein. Lane 2: GST. Load: 50 ng per lane. Primary antibody: Mouse anti-GSTM1 Monoclonal Antibody at 1:1,000 overnight at 4C. Secondary antibody: Peroxidase conjugated Rb-a-Ms IgG at 1:40,000 for 30 min at RT. Block: MB-070 for 30 min at RT. Predicted/Observed size: 27 kDa, 27 kDa for GSTM1. |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$549.00
Supplier Page
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