FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NB600-1335 (View supplier product page)
	Size	0.1 ml
	Price	$399.00
	Antigen	CHOP
	Clone	9C8
	Host	Mouse
	Isotype	IgG2b κ
	Conjugate	Unconjugated
	Target Species	Human, Mouse, Primate, Rat
	Applications	WB, IHC, ICC/IF, IP, IHC-P, Gel Shift, FC, ELISA, ChIP
	Description	Mouse GADD153/CHOP antibody [Purified] detects Human, Mouse, Rat, Primate

	CHOP	This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]

$399.00
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CHOP Monoclonal / Unconjugated / 9C8