EphB2 Polyclonal / Unconjugated /

Citations: (2)
Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-55398 (View supplier product page)
Size 0.1 mg
Price $399.00
Antigen EphB2
Clone
Host Goat
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications WB, ELISA
Description This antibody is expected to recognise both reported isoforms ( NP_059145.2 and NP_004433.2).
About EphB2 and Purified
EphB2 This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
Citations
PMID 16626680
PMID 17428795
Additional
Sources
Reviews & Ratings
Purified Excitation and Emission Spectra