EDAR Monoclonal / Unconjugated / ED5

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-64609 (View supplier product page)
Size 125 μg
Price $299.00
Antigen EDAR
Clone ED5
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Mouse (Negative), Rat
Applications IHC, IHC-Fr
Description ED5 staining reveals a web-like pattern in B cell follicles, representing the follicular dendritic cells. Mesangial cells in the kidney are also ED5-positive.
About EDAR and Purified
EDAR This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra