DUSP12 Polyclonal / Unconjugated /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-84961 (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen DUSP12
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC, IHC-P
Description Specificity of human DUSP12 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
About DUSP12 and Purified
DUSP12 The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008]
Images
  DUSP12 Purified Novus Biologicals, a Bio-Techne brand antibody anti target:Human host:Rabbit isotype:IgG clone: Immunohistochemistry-Paraffin: DUSP12 Antibody [NBP1-84961] - Staining of human colon shows stron...

Immunohistochemistry-Paraffin: DUSP12 Antibody [NBP1-84961] - Staining of human colon shows strong luminal membranous and cytoplasmic positivity in glandular cells.
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Purified Excitation and Emission Spectra