FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP2-13893 (View supplier product page)
	Size	0.1 ml
	Price	$519.00
	Antigen	CYP21A2
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human
	Applications	WB, IHC, IHC-P
	Description	Specificity of human CYP21A2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

	CYP21A2	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

		Immunohistochemistry-Paraffin: CYP21A2 Antibody [NBP2-13893] - Staining of human kidney.
		Immunohistochemistry-Paraffin: CYP21A2 Antibody [NBP2-13893] - Staining of human adrenal gland, cerebral cortex, kidney and testis using Anti-CYP21A2 antibody NBP2-13893 (A) shows similar protein distribution across tissues to independent antibody NBP2-38698 (B).
		Immunohistochemistry-Paraffin: CYP21A2 Antibody [NBP2-13893] - Staining of human cerebral cortex.
		Immunohistochemistry-Paraffin: CYP21A2 Antibody [NBP2-13893] - Staining of human pancreas shows low expression as expected.
		Immunohistochemistry-Paraffin: CYP21A2 Antibody [NBP2-13893] - Staining of human adrenal gland shows high expression.
		Immunohistochemistry-Paraffin: CYP21A2 Antibody [NBP2-13893] - Staining in human adrenal gland and pancreas tissues using anti-CYP21A2 antibody. Corresponding CYP21A2 RNA-seq data are presented for the same tissues.
		Western Blot: CYP21A2 Antibody [NBP2-13893] - Analysis in human adrenal gland tissue.
		Immunohistochemistry-Paraffin: CYP21A2 Antibody [NBP2-13893] - Staining of human testis.