FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP2-24770 (View supplier product page)
	Size	0.1 mg
	Price	$399.00
	Antigen	Cyclophilin B
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Bovine, Canine, Equine, Human, Mouse, Porcine, Primate, Rat
	Applications	WB, Knockout Validated
	Description	Rabbit Cyclophilin B antibody [Purified] detects Human, Mouse, Rat, Porcine, Bovine, Canine, Equine, Primate

	Cyclophilin B	The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]

		Knockout Validated: Cyclophilin B Antibody [NBP2-24770] - Western blot shows lysates of HeLa human cervical epithelial carcinoma parental cell line and Cyclophilin B knockout (KO) HeLa cell line. PVDF membrane was probed with 1:1000 of Rabbit Anti-Human Cyclophilin B Polyclonal Antibody (Catalog # NBP2-24770) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog #HAF008). Specific band was detected for Cyclophilin B at approximately 22 kDa (as indicated) in the parental HeLa cell line, but is not detectable in the knockout HeLa cell line. This experiment was conducted under reducing conditions.
		Western Blot: Cyclophilin B Antibody [NBP2-24770] - analysis of Cyclophilin B in A) HeLa cell lysate and B) 293 cell lysate using this antibody. 5 and 2 ug/ml, respectively. I goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.