FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP1-86055 (View supplier product page)
	Size	0.1 ml
	Price	$519.00
	Antigen	CTPS2
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human, Mouse, Rat
	Applications	WB, IHC, ICC/IF, IHC-P
	Description	Specificity of human CTPS2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

	CTPS2	The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

		Immunohistochemistry-Paraffin: CTPS2 Antibody [NBP1-86055] - Staining of human colon shows strong cytoplasmic and nuclear positivity in glandular cells.
		Immunocytochemistry/Immunofluorescence: CTPS2 Antibody [NBP1-86055] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
		Western Blot: CTPS2 Antibody [NBP1-86055] - Analysis in human cell line HEK 293.
		Western Blot: CTPS2 Antibody [NBP1-86055] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.