FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP1-83042 (View supplier product page)
	Size	0.1 ml
	Price	$549.00
	Antigen	CCT5
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human, Mouse, Rat
	Applications	WB, IHC, ICC/IF, IHC-P
	Description	Specificity of human, mouse, rat CCT5 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

	CCT5	The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]

		Immunohistochemistry-Paraffin: CCT5 Antibody [NBP1-83042] - Staining of human liver shows low expression as expected.
		Immunohistochemistry-Paraffin: CCT5 Antibody [NBP1-83042] - Staining of human testis shows high expression.
		Western Blot: CCT5 Antibody [NBP1-83042] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).
		Immunohistochemistry-Paraffin: CCT5 Antibody [NBP1-83042] - Staining of human colon.
		Immunocytochemistry/Immunofluorescence: CCT5 Antibody [NBP1-83042] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli & cytosol.
		Immunohistochemistry-Paraffin: CCT5 Antibody [NBP1-83042] - Staining of human cerebral cortex.
		Western Blot: CCT5 Antibody [NBP1-83042] - Analysis using Anti-CCT5 antibody NBP1-83042 (A) shows similar pattern to independent antibody NBP1-83043 (B).
		Immunohistochemistry-Paraffin: CCT5 Antibody [NBP1-83042] - Staining in human testis and liver tissues using anti-CCT5 antibody. Corresponding CCT5 RNA-seq data are presented for the same tissues.
		Immunohistochemistry-Paraffin: CCT5 Antibody [NBP1-83042] - Staining of human cerebral cortex, colon, liver and testis using Anti-CCT5 antibody NBP1-83042 (A) shows similar protein distribution across tissues to independent antibody NBP1-83043 (B).