CCR10 Monoclonal / Unconjugated / 248918R
CCR10 Monoclonal / Unconjugated / 248918R
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | MAB2815R-SP (View supplier product page) | |
| Size | 25 μg | |
| Price | $159.00 | |
| Antigen | CCR10 | |
| Clone | 248918R | |
| Host | Rat | |
| Isotype | IgG2a | |
| Conjugate | Unconjugated | |
| Target Species | Mouse | |
| Applications | FC, CyTOF | |
| Description | Mouse CCR10 Antibody |
About CCR10 and Purified
| CCR10 | Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008] |
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Images
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Detection of CCR10 in HEK293 Human Cell Line Transfected with Mouse CCR10 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) mouse CCR10 or (B) irrelevant transfectants and eGFP was stained with Rat Anti-Mouse CCR10 Monoclonal Antibody (Catalog # MAB2815R) or Rat IgG2A Isotype Control (Catalog # MAB006, data not shown) followed by Allophycocyanin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0113). View our protocol for Staining Membrane-associated Proteins. |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$159.00
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