FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP2-38772 (View supplier product page)
	Size	0.1 ml
	Price	$529.00
	Antigen	Catalase
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human
	Applications	WB, IHC, ICC/IF, IHC-P
	Description	Specificity of human Catalase antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

	Catalase	This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]

		Immunohistochemistry: Catalase Antibody [NBP2-38772] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.
		Western Blot: Catalase Antibody [NBP2-38772] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG. Lane 4: Human Plasma. Lane 5: Human liver tissue
		Immunocytochemistry/Immunofluorescence: Catalase Antibody [NBP2-38772] - Immunofluorescent staining of human cell line PC-3 shows localization to vesicles.
		Immunohistochemistry-Paraffin: Catalase Antibody [NBP2-38772] - Staining in human liver and pancreas tissues using anti-CAT antibody. Corresponding CAT RNA-seq data are presented for the same tissues.
		Immunohistochemistry-Paraffin: Catalase Antibody [NBP2-38772] - Staining of human lymph node.
		Immunohistochemistry-Paraffin: Catalase Antibody [NBP2-38772] - Staining of human bone marrow, liver, lymph node and pancreas using Anti-CAT antibody NBP2-38772 (A) shows similar protein distribution across tissues to independent antibody NBP2-38646 (B).
		Immunohistochemistry-Paraffin: Catalase Antibody [NBP2-38772] - Staining of human pancreas shows low expression as expected.
		Immunohistochemistry-Paraffin: Catalase Antibody [NBP2-38772] - Staining of human bone marrow.