CAMLG Polyclonal / Unconjugated /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: H00000819-B01P (View supplier product page)
Size 0.05 mg
Price $519.00
Antigen CAMLG
Clone
Host Mouse
Isotype IgG
Conjugate Unconjugated
Target Species Human, Rat
Applications WB
Description CAMLG - calcium modulating ligand,
About CAMLG and Purified
CAMLG The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra