BMP-6 Monoclonal / Unconjugated / 74219.11

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB120-10859 (View supplier product page)
Size 0.1 mg
Price $399.00
Antigen BMP-6
Clone 74219.11
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Target Species Human
Applications WB, ELISA, Block/Neutralize
Description This shows less than 5 % cross-reactivity with recombinant human BMP5 and BMP7 and no cross-reactivity with recombinant human BMP2 and BMP4 under reducing conditions.
About BMP-6 and Purified
BMP-6 This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016]
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Purified Excitation and Emission Spectra