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BMI1 Monoclonal / Unconjugated / JJ093-3

Citations: (1)

Product Details

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP2-67916 (View supplier product page)
	Size	100 ul
	Price	$410.00
	Antigen	BMI1
	Clone	JJ093-3
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human, Rat
	Applications	WB, IHC, ICC/IF, IHC-P
	Description	BMI-1 Antibody (JJ093-3)

About BMI1 and Purified

	BMI1	This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015]

Images

		Immunocytochemistry/Immunofluorescence: BMI-1 Antibody (JJ093-3) [NBP2-67916] - Staining Bmi1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
		Immunohistochemistry-Paraffin: BMI-1 Antibody (JJ093-3) [NBP2-67916] - Analysis of paraffin-embedded human tonsil tissue using anti-Bmi1 antibody. Counter stained with hematoxylin.
		Immunohistochemistry-Paraffin: BMI-1 Antibody (JJ093-3) [NBP2-67916] - Analysis of Bmi1 on different lysates using anti-Bmi1 antibody at 1/1,000 dilution. Positive control: Lane 1: K562 Lane 2: PC-12
		Immunohistochemistry-Paraffin: BMI-1 Antibody (JJ093-3) [NBP2-67916] - Analysis of paraffin-embedded human breast carcinoma tissue using anti-Bmi1 antibody. Counter stained with hematoxylin.
		Immunocytochemistry/Immunofluorescence: BMI-1 Antibody (JJ093-3) [NBP2-67916] - Staining Bmi1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
		Immunohistochemistry-Paraffin: BMI-1 Antibody (JJ093-3) [NBP2-67916] - Analysis of paraffin-embedded human lung cancer tissue using anti-Bmi1 antibody. Counter stained with hematoxylin.
		Immunohistochemistry-Paraffin: BMI-1 Antibody (JJ093-3) [NBP2-67916] - Analysis of paraffin-embedded rat smooth muscle tissue using anti-Bmi1 antibody. Counter stained with hematoxylin.
		Immunocytochemistry/Immunofluorescence: BMI-1 Antibody (JJ093-3) [NBP2-67916] - Staining Bmi1 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

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