FluoroFinder

Bestrophin 1 Polyclonal / Unconjugated /

Product Details

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP2-56225 (View supplier product page)
	Size	100 ul
	Price	$519.00
	Antigen	Bestrophin 1
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human
	Applications	IHC, IHC-P
	Description	Specificity of human Bestrophin 1 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

About Bestrophin 1 and Purified

	Bestrophin 1	This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]

Images

Immunohistochemistry-Paraffin: Bestrophin 1 Antibody [NBP2-56225] - Staining of human retina shows strong membranous positivity in retinal pigment epithelium.

Citations

	Additional Sources

Reviews & Ratings

Submit a Review

Purified Excitation and Emission Spectra

$519.00
Supplier Page

Submit a Review