FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP1-85857 (View supplier product page)
	Size	0.1 ml
	Price	$519.00
	Antigen	BCDIN3D
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human
	Applications	WB, IHC, ICC/IF, IHC-P
	Description	Specificity of human BCDIN3D antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

	BCDIN3D	This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs. [provided by RefSeq, Apr 2017]

		Western Blot: BCDIN3D Antibody [NBP1-85857] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp
		Immunohistochemistry-Paraffin: BCDIN3D Antibody [NBP1-85857] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.
		Immunocytochemistry/Immunofluorescence: BCDIN3D Antibody [NBP1-85857] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.