FluoroFinder

	Supplier	Novus Biologicals, a Bio-Techne brand
	Catalog #:	NBP1-46223 (View supplier product page)
	Size	0.1 ml
	Price	$449.00
	Antigen	API5
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Unconjugated
	Target Species	Human, Mouse
	Applications	WB, IHC, IP, IHC-P

	API5	This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

		Western Blot: API5 Antibody [NBP1-46223] - Whole cell lysate from HeLa, 293T, and mouse NIH3T3 cells. API5 was also immunoprecipitated by rabbit anti-API5 antibody NBP1-46224.
		Immunohistochemistry: API5 Antibody [NBP1-46223] - Sample: FFPE section of human breast carcinoma (left) and mouse teratoma (right). Antibody: Affinity purified rabbit anti-API5 used at a dilution of 1:1,000 (0.2 ug/ml) and 1:200 (1 ug/ml) Detection: DAB staining using Immunohistochemistry Accessory Kit .