ADAMTS5 Polyclonal / Unconjugated /

Product Details
Supplier R&D Systems
Catalog #: AF2198-SP (View supplier product page)
Size 25 μg
Price $149.00
Antigen ADAMTS5
Clone
Host Goat
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications WB, IP
Description Human ADAMTS5 Antibody
About ADAMTS5 and Purified
ADAMTS5 This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016]
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Purified Excitation and Emission Spectra