CD49c Monoclonal / Janelia Fluor 646 / 54B3

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-97732JF646 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen CD49c
Clone 54B3
Host Mouse
Isotype IgG1
Conjugate Janelia Fluor 646
Target Species Human
Applications IHC, ICC/IF, IHC-Fr
Description 54B3 recognizes specifically the cytoplasmic domain of integrin subunit alpha3B. The monoclonal antibody reacts with Human tissues. A broader species reactivity is expected because of the conserved nature of the epitope.
About CD49c and Janelia Fluor 646
CD49c The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015]
Janelia Fluor 646 Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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Janelia Fluor 646 Excitation and Emission Spectra