Cyclin A2 Monoclonal / Janelia Fluor 646 / E67

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-34613JF646 (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen Cyclin A2
Clone E67
Host Mouse
Isotype IgG2a κ
Conjugate Janelia Fluor 646
Target Species Bovine, Human, Mouse, Mustelid, Primate
Applications FC, IHC, ICC/IF, IHC-P, IHC-Fr
Description It recognizes a protein of 54kDa, which is identified as cyclin A. Its epitope is located amino acids 144-148 of human Cyclin A2. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while cyclin B is a critical regulator of mitosis. Mutation or disruption of normal cyclin A expression causes cells to arrest in G2-phase.
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Reviews & Ratings
Janelia Fluor 646 Excitation and Emission Spectra