CD11b Monoclonal / Janelia Fluor 646 / ITGAM/3340

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-34573JF646 (View supplier product page)
Size 100 μl
Price $429.00
Antigen CD11b
Clone ITGAM/3340
Host Mouse
Isotype IgG2a κ
Conjugate Janelia Fluor 646
Target Species Human
Applications FC, IHC, ICC/IF, IHC-Fr, ELISA
Description Mouse CD11b antibody [Janelia Fluor 646] detects Human
About CD11b and Janelia Fluor 646
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Janelia Fluor 646 Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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Janelia Fluor 646 Excitation and Emission Spectra