BMP-8b Monoclonal / Janelia Fluor 646 / 13000000

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-42693JF646 (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen BMP-8b
Clone 13000000
Host Mouse
Isotype IgG2a κ
Conjugate Janelia Fluor 646
Target Species Human
Applications ICC, IF
About BMP-8b and Janelia Fluor 646
BMP-8b This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]
Janelia Fluor 646 Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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Janelia Fluor 646 Excitation and Emission Spectra