EGF Receptor Monoclonal / Janelia Fluor 549 / GFR/1708

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-54330JF549 (View supplier product page)
Size 0.1 ml
Price $529.00
Antigen EGF Receptor
Clone GFR/1708
Host Mouse
Isotype IgG1
Conjugate Janelia Fluor 549
Target Species Human
Applications FC, IHC, ICC/IF, IHC-P
Description Mouse EGFR antibody [Janelia Fluor 549] detects Human
About EGF Receptor and Janelia Fluor 549
EGF Receptor The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020]
Janelia Fluor 549 Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.
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Janelia Fluor 549 Excitation and Emission Spectra